| abstract |
A method for inhibiting a protein kinase selected from the group consisting of AKT, checkpoint kinase, Aurora kinase, Pim kinase and tyrosine kinase using a pyrazolo [1,5-a] pyrimidine compound, and a method for inhibiting such a compound Use to provide a method of treating, preventing, inhibiting or ameliorating one or more diseases associated with protein kinases. In one aspect, the invention provides a method of inhibiting the activity of one or more kinases in a patient, wherein the kinase is from the group consisting of Akt kinase, checkpoint kinase, Pim kinase, and Aurora kinase. The method is selected, wherein a therapeutically effective amount of at least one compound, or a pharmaceutically acceptable salt, solvate, ester, isomer or prodrug of the compound is administered to a patient in need of the method. The step of administering. [Selection figure] None |