abstract |
Disclosed is a non-laboratory virus strain having improved oncolytic and / or gene delivery capabilities compared to a laboratory virus strain. [MEANS FOR SOLVING PROBLEMS] Modified by deletion of one or more of functional ICP34.5 coding gene, functional ICP6 coding gene, functional glycoprotein H coding gene, and functional thymidine kinase coding gene in HSV strain Or a non-laboratory virus strain in which the virus lacks a functional gene equivalent to one of the HSV genes in a strain other than HSV. [Selection figure] None |