| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_43399fa07c52d859e9e58cbe0d92f6c8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e5755139ddbbc30f36a32fecde0e9510 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-08 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-30
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-395
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
| filingDate |
2011-10-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c0aff1b72fe01a4c5a8541ed90d09d51
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4eac4472618bdcf083835d6fe235c886
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3ea3559d7f414c8c70156d1ca05b52bd
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a4cf11ac07c9105b06cfb6e95a5520e0
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_18a67edd568d7c9d45d6bb9717f18dea
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a69f7671e2b25cbfc2f1d41eb25a027b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3154f4cb19ed1be9b56b4bd69513394a |
| publicationDate |
2012-04-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
JP-2012067106-A |
| titleOfInvention |
Glycosylated antibody |
| abstract |
A monoclonal antibody derived from a parent monoclonal antibody that recognizes Lewis Y antigen, or a derivative or fragment thereof is provided. The monoclonal antibody or derivative or fragment thereof has a bipartite hybrid N-glycosylation pattern in the Fc region or Fc region equivalent, wherein the antibody has at least a 10-fold increase in ADCC activity and at least a 10% decrease. It has CDC activity. A humanized antibody having the antibody-differentiated N-acetylglucosamine group. [Selection figure] None |
| priorityDate |
2011-10-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |