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publicationDate 2012-02-09-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber JP-2012025955-A
titleOfInvention Adhesive gel derived from crosslinked hyaluronan and / or hylan, its preparation and use
abstract An adhesive gel derived from cross-linked hyaluronan or hylan, its preparation and use. Disclosed is a highly elastic and tacky gel formed by crosslinking hyaluronan or hylan, a salt or derivative thereof using divinyl sulfone (DVS) as a crosslinking agent. Also disclosed is a viscoelastic fluid in which an alkyl sulfone group is covalently bonded to the polymer backbone formed by monofunctionalization of the cross-linking monomer DVS with hyaluronan and / or hylan. Mechanical properties such as hardness and tack values are specified by the rheological properties of the gel. A method of preparing such a product is also disclosed. They are used in many applications as injectable and / or implantable devices and as drug delivery systems. [Selection figure] None
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