http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2011530487-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C215-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D265-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D265-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C213-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C215-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D265-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C213-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C213-00 |
| filingDate | 2008-08-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2011-12-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-2011530487-A |
| titleOfInvention | Substances and methods for the stereoselective synthesis of variolamines |
| abstract | The present invention provides a practical method for mass-producing high-purity variolamine. The present invention relates to an intermediate compound for preparing variolamine and a method for preparing the same. This intermediate compound has the chemical structural formula shown in the following formula (21). Bicyclic carbamate derivatives of formula (21) are produced by C-acylation of compounds of formula (14) containing isomers, followed by R group removal from compounds of formula (21) and / or A variolamine having a purity of 99% or more is obtained by hydrolysis. The high-purity variolamine obtained in the present invention can be further used for the preparation of high-purity diabetes therapeutic drug voglibose. The obtained voglibose has a purity of 99.5% or more as measured by HPLC. [Selection figure] None |
| priorityDate | 2008-08-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 129.