http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2011530486-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-341 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D307-12 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L31-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K36-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-341 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-02 |
| filingDate | 2009-07-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2011-12-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-2011530486-A |
| titleOfInvention | Pharmaceutical composition comprising lignans and derivatives thereof for the treatment of hyperplastic diseases |
| abstract | The present invention relates to pharmaceutical compositions comprising certain compounds obtainable from Leontopodium alpinum Cass. (Edelweiss). The compound is leoligin (= (2S, 3R, 4R) -4- (3,4-dimethoxybenzyl) -2- (3,4-dimethoxyphenyl) tetrahydrofuran-3-yl] methyl (2Z) -2-methylbuta- 2-enoate]). Corresponding means and methods for the medical use of said compounds have been described. The present invention also provides a medical device comprising, containing, or in contact with the compounds. The compounds provided herein can be used in particular in the treatment of hyperplastic disorders, in particular intimal hyperplasia, such as stenosis, restenosis, atherosclerosis. Also described herein is the use of these compounds in the treatment of proliferative disorders such as leukemia, prostate cancer and lung cancer. [Selection figure] None |
| priorityDate | 2008-07-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 329.