http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2011528693-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D239-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C255-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D417-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C255-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C253-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C271-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D415-00 |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07B61-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D239-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C253-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C255-30 |
| filingDate | 2009-07-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2011-11-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-2011528693-A |
| titleOfInvention | Novel synthesis of substituted 4-amino-pyrimidines |
| abstract | The present invention relates to a process for the preparation of a compound of structural formula IV wherein R 1 is an amino protecting group and R 2 is hydrogen or C 1-10 alkyl, comprising a) a compound of structural formula Ia (formula Medium M + is preferably a cation selected from the group consisting of Li + , Na + , K + , 1 / 2Mg 2+ and 1 / 2Zn 2+ ) (structure Ia) in the solvent with the ammonium salt NH 4 Reacting with + X − where X − is preferably an anion selected from the group consisting of chloride, bromide, sulfate and acetate to give a compound of structural formula II; b) of structural formula II Reacting the compound with a nitrile R 2 —CN in the presence of a base to give a compound of structural formula IV. The present invention further compound of formula II, and also relates to its use for the production of vitamin B 1. |
| priorityDate | 2008-07-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 24.