| abstract |
The present invention relates to novel products of formula (I): wherein n = 0, 1 or 2; X is H, Hal or alk; R is H, NH 2 , NHalk or N (alk) in There 2; Ra is optionally substituted all, H, Hal, -O- cycloalkyl, -O- alkyl, -O- aryl, -O- heteroaryl, -NRd (cycloalkyl), - NRd ( Alkyl), -NRd (aryl), -NRd (heteroaryl), alkyl, cycloalkyl, heterocycloalkyl, aryl or heteroaryl; Rb is H, Rc, -COORc-CO-Rc or -CO-NRcRd Rc is all optionally substituted alkyl, cycloalkyl, heterocycloalkyl, aryl and heteroaryl; Rd is H, be alk or cycloalkyl; These products, as a medicament, in particular as MET inhibitor are all isomeric forms and salts. |