http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2011528038-A
Outgoing Links
Predicate | Object |
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classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2300-606 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2300-258 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-0041 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-34 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7088 |
filingDate | 2009-07-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2011-11-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | JP-2011528038-A |
titleOfInvention | Medical device and nucleic acid delivery method |
abstract | Embodiments of the present invention include devices for releasing nucleic acids and related methods. In one embodiment, the present invention comprises an active ingredient elution coating comprising a polymer matrix, a cationic carrier disposed with the matrix, and an active ingredient disposed within the matrix, wherein the active ingredient is substantially the same as the cationic carrier. Contains uncomplexed nucleic acid. In one embodiment, the present invention combines a step of selecting a concentration of cationic carrier corresponding to a desired elution profile, a matrix-forming polymer, an active ingredient, a solvent, and a cationic carrier to select a selected concentration of cationic carrier. A method for producing an implantable medical device, comprising forming a coating composition having a carrier, wherein the active ingredient comprises a nucleic acid and depositing the coating composition on the surface of a substrate. Other embodiments are also included herein. |
priorityDate | 2008-07-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 97.