abstract |
Soluble hybrid Fcγ receptor (FcγR) polypeptide compositions and related methods for treating IgG-mediated and immune complex-mediated inflammation using such polypeptides are disclosed. Related compositions and methods for producing soluble hybrid FcγR polypeptides are also disclosed. In another aspect, the present invention provides a method of reducing IgG-mediated or immune complex-mediated inflammation, the method comprising a sufficient amount of a soluble FcγR composition to reduce inflammation. Administering to a mammal having inflammation. |