http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2011524864-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D519-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D498-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-18 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D519-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-437 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-5377 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K49-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D498-04 |
| filingDate | 2009-05-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2011-09-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-2011524864-A |
| titleOfInvention | Novel substituted azabenzoxazole |
| abstract | The present invention relates to a novel amyloid-binding compound of formula (I) and a method for measuring the effect of the compound by measuring changes in amyloid plaque levels in a surviving patient. More specifically, the present invention enables the diagnosis of Alzheimer's disease by using the compounds of the present invention as a positron emission tomography (PET /) imaging tracer for studying amyloid deposition in the brain in vivo. Regarding the method. That is, the present invention relates to the use of a novel amyloid-binding compound as a diagnostic agent. The present invention further relates to a method for measuring the clinical efficacy of a therapeutic agent for Alzheimer's disease. Specifically, the present invention provides a novel aryl or heteroaryl substituted azabenzoxazole derivative wherein X is 0 or S, and A and Y are independently N or CH. The invention relates to pharmaceutically acceptable salts, solvates or in vivo hydrolysable esters, compositions, and therapeutic uses and processes for the preparation of these compounds. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-7126541-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20170046173-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-102456946-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2019123675-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2017528519-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2021059576-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-102586736-B1 |
| priorityDate | 2008-05-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 311.