| abstract |
The present invention relates to a method for assessing an unfavorable or conversely favorable cancer prognosis in a subject, the method comprising a mutated natural cytotoxicity-inducing receptor 3 (NCR3) nucleic acid, an abnormal relative amount of at least one of Detecting in a sample from a subject the presence of a specific natural killer p30 (NKp30) RNA transcript isoform, and / or an abnormal natural killer p30 (NKp30) expression or activity of at least one specific NKp30 protein isoform. The presence of aberrant expression or activity of an NCR3 nucleic acid containing, mutated, an abnormal relative amount of at least one specific NKp30 RNA transcript isoform, or at least one specific NKp30 protein isoform is a prognosis of cancer in a subject Shows |