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filingDate 2009-06-10-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2011-08-25-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber JP-2011523937-A
titleOfInvention IQGAP3 epitope peptide and vaccine containing the same
abstract In this specification, the peptide vaccine with respect to cancer is described. In particular, the present invention describes IQGAP3-derived epitope peptides that induce CTL. The present invention also provides established CTLs that specifically recognize HLA-A24 positive target cells or HLA-A02 positive target cells pulsed with the peptide. Also provided are antigen presenting cells and exosomes that present any of the peptides, and methods for inducing antigen presenting cells. The present invention further provides a pharmaceutical agent comprising an IQGAP3 polypeptide or a polynucleotide encoding the same, and exosomes and antigen-presenting cells as active ingredients. Furthermore, the present invention relates to treatment of cancer (tumor) using IQGAP3 polypeptide, polynucleotide encoding the polypeptide, exosome or antigen-presenting cell presenting the polypeptide, or pharmaceutical agent of the present invention. Methods are provided for / and preventing (ie, preventing) and / or preventing its recurrence after surgery, as well as methods for inducing CTLs and methods for inducing anti-tumor immunity. Targeted cancers include but are not limited to kidney cancer, esophageal cancer, gastric cancer, lung cancer, breast cancer, bladder cancer and pancreatic cancer.
priorityDate 2008-06-11-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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