| abstract |
The present invention relates to methods for inhibiting or treating cancer, in particular, one or more methods for inhibiting or treating colorectal cancer, breast cancer, prostate cancer and / or lung cancer. The therapy uses the use of non-cytotoxic proteases, which are targeted to growth hormone secreting cells such as pituitary cells. When so delivered, the protease is internalized and inhibits growth hormone secretion / transmission from the cell. The invention also relates to polypeptides and nucleic acids for use in this method. |