| abstract |
The present invention provides the following formula (I): [Where: R 1 and R 3 each independently represents a methoxy group optionally substituted with one or more fluorine atoms, R 2 and R 4 each independently represents a hydrogen atom or a methoxy group optionally substituted with one or more fluorine atoms, A represents a ring selected from the group consisting of aryl and heteroaryl groups, which ring may be substituted or fused with a heterocycle, X represents a nitrogen atom or a CH group, Z 1 represents a hydrogen atom or a halogen atom (preferably fluorine), and Z 2 represents a hydrogen atom, a halogen atom (preferably fluorine), a C 1 -C 4 alkyl, an aryl group, —CN, SO 2 NR 12 R 13 , —SO 2 R 9 , —COOR 15 or —COR 15 group. Represents] And pharmaceutically acceptable salts, isomers and prodrugs thereof. |