abstract |
A suitable composition for administration to a patient comprising a) a compound represented by I or a pharmaceutically acceptable salt thereof and b) a pharmaceutically acceptable excipient. Wherein R 1 is selected from the group consisting of alkylene-R 5 -R 6 -R 2 , -R 6 -C (O) -phenyl, -R 6 -phenyl, alkyl, alkenyl or alkynyl, wherein phenyl Each independently may be substituted with one or more groups selected from halo, alkyl, CN or NO 2 , R 2 is substituted at 1, 2 or 3 positions with halo, CN or alkyl R 3 is independently selected from the group consisting of H, halo, CN and NO 2 , and R 4 and R 5 are selected from the group consisting of thio, sulfonyl or sulfinyl. And R 6 is alkylene or a bond. |