abstract |
The present invention provides formulas (I), (Ik), (Iq 1-21 ), (Ir 1-21 ), (Ir 1-21 ), ( Is 1-21 ), a novel compound of (It 1-7 ), a pharmaceutically acceptable salt thereof, and a pharmaceutical composition thereof. The present invention further relates to pharmaceutical compositions of the novel compounds and methods for their use in reducing or controlling intracellular cortisol production or inhibiting the conversion of cortisone to cortisol intracellularly. |