| Predicate |
Object |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2430-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61F2002-3096
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2300-414
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61F2310-00293
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61F2310-00365
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61F2002-3092
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61F2210-0004
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61F2002-2817
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61F2002-30062 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-54
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-56
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-40
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61F2-2803 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-00 |
| filingDate |
2009-03-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate |
2011-06-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
JP-2011517993-A |
| titleOfInvention |
Rigid bone graft substitute |
| abstract |
The bone graft substitute includes a porous matrix that is at least partially covered by a reinforcing outer layer. The porous matrix may be a collagen-ceramic composite and the reinforcing outer layer can be formed from highly cross-linked collagen. The implant may also include one or more reinforcing ribs that can be made from calcium phosphate or dense collagen. Furthermore, the bone graft substitute preferably comprises an effective amount of a bioactive agent, such as BMP-2, rhBMP-2, or a functional fragment thereof. The bioactive agent is preferably disposed in the porous matrix. [Selection figure] None |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11355231-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11424023-B2 |
| priorityDate |
2008-04-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |