| abstract |
The present invention is directed to compounds of formula I which are antagonists of the CGRP receptor and are useful in the treatment or prevention of diseases involving CGRP such as migraine. (Where, variables A 1 , A 2 , A 3 , A 4 , A 5 , A 6 , A 7 , A 8 , G 1 , G 2 , G 3 , G 4 , J, Q, E a , E b , E c , R 6 , R 7 , R PG and Y are as described herein). The present invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases involving CGRP. |