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filingDate 2009-03-05-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2011-04-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber JP-2011512848-A
titleOfInvention Living organisms that produce primary alcohol
abstract The present invention provides a non-naturally occurring microorganism having a microorganism with at least one exogenous gene insertion and / or one or more gene disruptions that result in the production of primary alcohols. Methods for producing long chain alcohols include culturing these non-naturally occurring microorganisms. In some aspects, embodiments disclosed herein include at least one exogenous nucleic acid encoding a malonyl-CoA independent FAS pathway enzyme expressed in an amount sufficient to produce a primary alcohol. A non-naturally occurring microorganism comprising a microorganism having a malonyl-CoA independent fatty acid synthesis (FAS) pathway and an acyl reduction pathway, wherein the malonyl-CoA independent FAS pathway comprises Has ketoacyl-CoA thiolase, 3-hydroxyacyl-CoA dehydrogenase, enoyl-CoA hydratase and enoyl-CoA reductase.
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