abstract |
The present invention relates to a compound of formula (I) wherein the substituents are as described in claim 1. The compounds of formula (I) have been found to be modulators of amyloid β and thus diseases associated with β-amyloid deposition in the brain, in particular Alzheimer's disease, as well as cerebral amyloid angiopathy, It may be useful for the treatment or prevention of other diseases such as Dutch hereditary amyloid cerebral hemorrhage (HCHWA-D), multiple cerebral infarction dementia, boxer dementia and Down's syndrome. |