Predicate |
Object |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0019 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-21 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-61 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-50 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-198 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K33-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-704 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-407 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
filingDate |
2009-01-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate |
2011-04-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
JP-2011511002-A |
titleOfInvention |
Intralymphatic chemotherapy drug carrier |
abstract |
A chemotherapeutic composition for subcutaneous administration can be constructed that is due to preferential lymphatic accumulation but also provides a therapeutic systemic concentration that is not toxic. The composition may comprise a pharmaceutically acceptable carrier and a nanoconjugate configured for preferential lymphatic accumulation after subcutaneous administration. The nanoconjugate may comprise a nanocarrier configured for preferential lymphatic accumulation after subcutaneous or intrastitial administration and a plurality of chemotherapeutic agents coupled to the nanocarrier. The nanoconjugate may have a dimension of about 10 to about 50 nm. The nanoconjugate may also be loaded with about 10 to about 50% w / w chemotherapeutic agent. The nanocarrier may be a hyaluronic acid polymer of about 3 kDa to about 50 kDa. Alternatively, the nanocarrier may be a dendrimer. [Selection] Figure 1 (A) |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2022508458-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-7199794-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2016216454-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-7235870-B2 |
priorityDate |
2008-01-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |