| abstract |
The present invention relates to suspension formulations, particularly formulations for delivering pharmaceutically active agents in aerosol form using a spray or aerosol device such as a pressurized metered dose inhaler (pMDI). The formulation may be for pulmonary, nasal, buccal or topical administration but is preferably for pulmonary inhalation. Suspension formulations include active agent particles, propellants, one or more suspension stabilizers (amino acids, leucine, sugars, disaccharides, trehalose) and / or co-solvents (alcohol, ethanol). |