http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2011510291-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6857 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-543 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-545 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-548 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-553 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-564 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-37 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53 |
| filingDate | 2008-01-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2011-03-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-2011510291-A |
| titleOfInvention | Methods and kits for detecting antibodies against therapeutic antibodies |
| abstract | The present invention relates to the fields of immunology and immunological diagnostics. More particularly, the invention relates to the detection of antibody formation in a subject treated with a therapeutic antibody. What is provided is a diagnostic method for determining the presence or absence of an IgG antibody against a therapeutic antibody in a subject, the following steps: a) obtaining a solid support that can bind to the constant region of the IgG antibody; b) the therapeutic antibody Isolating a sample from a subject to be tested for the presence or absence of IgG antibodies against c; c) incubating the carrier with the sample under conditions suitable to immobilize IgG antibodies on the solid carrier; d Between the antigenic fragment wherein the immobilized antibody is conjugated to a detectable label that lacks the constant region of the therapeutic antibody and between the at least a portion of the immobilized antibody and the antigenic fragment Incubating under conditions allowing complex formation, said incubation being non-therapeutic lacking the constant region Carried out in the presence of unlabeled antigenic fragment of the body, it is a diagnostic method. In addition, kits are provided for use in such methods. [Selection figure] None |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2017502285-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2014508930-A |
| priorityDate | 2008-01-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 67.