http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2011509302-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-496 |
| filingDate | 2009-01-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2011-03-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-2011509302-A |
| titleOfInvention | Pyrazolopyridines as kinase inhibitors |
| abstract | Formula I: These compounds are useful for the inhibition of CHK1 and / or CHK2. Compounds of formula I, and their stereoisomers and pharmaceutically acceptable for the in vitro, in situ and in vivo diagnosis, prevention or treatment of such disorders in mammalian cells or related pathological conditions A method of using the salt is disclosed. Another aspect of the present invention is a method for the prevention or treatment of a disease or disorder modulated by CHK1 and / or CHK2, comprising an effective amount of a compound of the present invention or a steric form thereof in a mammal in need of such treatment. Methods are provided that include administering an isomer or a pharmaceutically acceptable salt. Examples of such diseases and disorders include, but are not limited to, hyperproliferative disorders (eg, cancer), neurodegeneration, cardiac hypertrophy, pain, migraine and neurotraumatic diseases. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2015506957-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2017518383-A |
| priorityDate | 2008-01-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 533.