abstract |
The present invention is a method for modifying a biocompatible member, comprising the following steps: a) a biocompatible member at least partially coated with a metal oxide; and b) a portion of the member comprising the biocompatible member Treating at least a portion of the member coated with the metal oxide with an aqueous composition comprising oxalic acid, whereby a modified metal oxide is obtained. The invention also provides a biocompatible member: a) a microstructure comprising pits separated by a plateau and / or ridge; and b) a primary nanostructure overlying the microstructure, wherein the primary The nanostructure relates to a biocompatible member comprising a substrate having a surface comprising: depressions arranged in a wavy shape. [Selection] Figure 5a |