abstract |
The present invention relates to a compound of formula (I), wherein X is a substituted phenyl group; R 1 is a hydrogen atom, a halogen, a (C 1 -C 6 ) alkoxy group, (C 1 -C 6) ) Represents an alkyl group or an NRaRb group; R 2 represents a hydrogen atom, an optionally substituted (C 1 -C 6 ) alkyl group, an optionally substituted (C 1 -C 6 ) alkoxy group, (C 2- C 6) alkenyl, (C 2 -C 6) alkynyl group, -CO-R 5 group, -CO-NR 6 R 7 group, -CO-O-R 8 group, -NR 9 -CO-R 10 group , —NR 11 R 12 group, —N═CH—NRaRb group, halogen atom, cyano, nitro, hydroxyiminoalkyl, alkoxyiminoalkyl group, (C 1 -C 6 ) alkylthio group, (C 1 -C 6 ) alkyl Sulfinyl group, (C 1 -C 6 ) al Killsulfonyl group, (((C 1 -C 6 ) alkyl) 3 ) silylethynyl group, —SO 2 —NR 9 R 10 group, optional by one or more groups independently selected from the following atoms or groups A phenyl group substituted by: halogen, (C 1 -C 6 ) alkoxy, cyano, NRaRb, —CO—R 5 , —CO—NR 6 R 7 , —CO—O—R 8 or one or more hydroxy or A (C 1 -C 6 ) alkyl group optionally substituted by an NRaRb group; R 3 represents a hydrogen atom, a (C 1 -C 6 ) alkyl group, a (C 1 -C 6 ) alkoxy group or a halogen atom; R 4 represents a hydrogen atom, a (C 1 -C 4 ) alkyl group, a (C 1 -C 4 ) alkoxy group or a fluorine atom, and this compound is in the form of an addition salt with a base or acid. The present invention can be used for therapy. |