| abstract |
The present invention relates to 17-hydroxy- of formula I (wherein R 4 , R 6a , R 6b , R 7 , R 15 , R 16a , R 16b , R 18 and Z have the meanings given in claim 1). It relates to 19-nor-21-carboxylic acid-steroid γ-lactone derivatives and their solvates, hydrates, stereoisomers and salts. Furthermore, the present invention relates to the use of these derivatives for the production of medical products for the treatment of oral contraception and pre-menopausal, post-menopausal and post-menopausal complaints and medical products containing said derivatives. The derivatives according to the invention have a progesterone action, and in a preferred case have an anti-mineralcorticoid action and a neutral to slight androgenic action. |