| abstract |
The present invention reduces cough in humans to reduce pain from pharyngitis in humans, to treat unpleasant sensations in human oropharynx, to treat unpleasant sensations in human upper respiratory tract And methods and devices for improving asthma, dyspnea, sleep apnea, snoring, or chronic obstructive pulmonary disease symptoms and signs in humans. According to the present invention, the active compound is delivered, preferably selectively delivered, to the patient's oropharynx, preferably the surface of the oropharynx, more preferably the oropharynx (LRO) below the palate. According to the present invention, the active compounds are those compounds of the formula: (wherein, -R is C 2 -C a 4 hydroxyalkyl or polyhydroxyalkyl) is. |