| abstract |
The present invention relates to a compound of formula (I) [Wherein R represents a (C 1 -C 6 ) alkyl or a halo (C 1 -C 6 ) alkyl group; Represents the group NR 4 R 5 or OR 8; when present, A and B, independently of one another, represent one or two carbon atoms, which carbon atoms are one or more hydrogen or (C 1 -C 6 ) alkyl. The (C 1 -C 6 ) alkyl group may be substituted; A + B represents at most 2 carbon atoms; R 1 is a hydrogen atom or (C 1 -C 6 R2 and R3 independently of each other represent a hydrogen atom or a (C 1 -C 6 ) alkyl group; this (C 1 -C 6 ) alkyl group may be substituted; R4 and R5, independently of one another, represent a hydrogen atom or a (C 1 -C 6) alkyl group, or together with the nitrogen atom which carries them, an azetidine, pyrrolidine, piperidine, azepane, piperazine, Homopipe Jin, morpholine, thiomorpholine, forms a heterocycle of thiomorpholine S- oxide or thiomorpholine S- dioxide type, this heterocycle may optionally be substituted by (C 1 -C 6) alkyl group; R6 and R7 are each optionally represents a phenyl group substituted; Y is a hydrogen atom, a halogen or a (C 1 -C 6) alkyl group, halo (C 1 -C 6) alkyl, (C 1 -C 6) alkoxy, halo (C 1 -C 6) alkoxy, (C 1 -C 6) alkyl S (O) represents a p or cyano group; R8 is a hydrogen atom, (C 1 -C 6) alkyl group, halo ( C 1 -C 6) alkyl group, an allyl group or a phenyl (C 1 -C 6) alkyl group, the phenyl group is substituted by one or two O-methyl group And p represents an integer selected from 0, 1 and 2], and provides compounds in the form of bases or addition salts with acids or bases . Preparation methods and therapeutic applications are also provided. |