http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2011506554-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4015 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P19-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D207-277 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4015 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P29-00 |
| filingDate | 2008-12-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2011-03-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-2011506554-A |
| titleOfInvention | 5-Oxo-3-pyrrolidinecarboxamide derivatives as P2X7 modulators |
| abstract | The present invention provides a compound of formula (IA) or a pharmaceutically acceptable salt thereof. Where R 1 represents C 1-4 alkyl, C 2-6 alkenyl, C 2-6 alkynyl, C 3-6 cycloalkyl, C 3-6 cycloalkylmethyl-, phenyl-X-, or heteroaryl. Each of which may be optionally substituted; X represents — (CR 12 R 13 ) n —; n represents 0 to 2; R 7 , R 8 , R 9 , R 10 , and R 11 Represents independently H, halogen, or cyano; or optionally substituted C 1-6 alkyl, C 2-6 alkenyl, C 2-6 alkynyl, or C 3-6 cycloalkyl; , R 7 , R 8 , R 9 , R 10 , and R 11 represent a group other than H, and at least one of R 7 and R 11 represents a group other than H; N-[(2,4-di Other than chlorophenyl) methyl] -5-oxo-1- (phenylmethyl) -3-pyrrolidinecarboxamide. The compounds and salts are thought to modulate P2X7 receptor function and be able to antagonize the action of ATP at the P2X7 receptor. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2016506915-A |
| priorityDate | 2007-12-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 320.