abstract |
An I-MsoI homing endonuclease mutant capable of cleaving a mutant I-MsoI site having fluctuations at positions ± 8 to ± 10, a vector encoding the mutant, a cell, an animal or a plant modified by the vector. Use of the I-MsoI endonuclease variants and derivative products described above for genetic engineering, genome therapy and antiviral therapy. [Selection figure] None |