abstract |
The use of β-glucan as an antigen for immunization against fungi is known. According to the present invention, β-glucan is administered with an adjuvant. Adjuvant improves immune response. Glucan is usually conjugated to a carrier. Suitable glucans include laminarin and curdlan. In one embodiment, (a) a glucan comprising β-1,3-linkage and / or β-1,6-linkage; and (b) an adjuvant (where component (b) is not a complete Freund's adjuvant and cholera toxin But not) is provided. |