http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2011503096-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C253-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D231-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F17-02 |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01J31-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07B61-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F19-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F17-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F15-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F15-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C253-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C255-58 |
| filingDate | 2008-11-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2011-01-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-2011503096-A |
| titleOfInvention | Process for preparing 2-amino-5-cyanobenzoic acid derivatives |
| abstract | A method of preparing a compound of formula 1 comprising the step of contacting a compound of formula 2 with at least one alkali metal cyanide of formula 3 and a compound of formula 4 is disclosed. [Chemical 1] Wherein R 1 is NHR 3 or OR 4 ; R 2 is CH 3 or Cl; R 3 is H, C 1 -C 4 alkyl, cyclopropyl, cyclopropylcyclopropyl, cyclopropylmethyl or methyl R 4 is H or C 1 -C 4 alkyl; X is Br, Cl or I; and R 5 , R 6 , R 7 , R 8 , R 9 and R 10 are As defined in this disclosure. And R 9 and R 10 together, comprising contacting a compound of Formula 5 wherein Y is Cl, Br or I with a cycloalkadiene bidentate ligand, at least one metal reducing agent and a nitrile solvent. Also disclosed are methods for preparing compounds of formula 4 that are cycloalkadiene bidentate ligands. Also, the step of preparing a compound of formula 4 by contacting a compound of formula 5 with a cycloalkadiene bidentate ligand and at least one metal reducing agent, then the reaction mixture comprising the compound of formula 4 and the formula Also disclosed is a method of preparing a compound of formula 1 comprising contacting a compound of formula 2 and at least one alkali metal cyanide of formula 3; and preparing a compound of formula 1 by the method disclosed above Further disclosed is a method for preparing a compound of formula 6 wherein R 15 , R 16 , R 17 and Z are as defined in the present disclosure using a compound of formula 1 . [Chemical 2] |
| priorityDate | 2007-11-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 160.