http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2011500023-A
Outgoing Links
Predicate | Object |
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classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-14 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-1138 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-713 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7088 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-113 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-713 |
filingDate | 2008-10-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2011-01-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | JP-2011500023-A |
titleOfInvention | Therapeutic siRNA molecules for reducing VEGFR1 expression in vitro and in vivo |
abstract | Improving the method for delivering RNAi-derived molecules in vivo is extremely important. It is also clear that delivering nucleic acid molecules that induce RNAi to the tissue as a target is crucial. It is also clear that the method of delivering nucleic acid molecules that induce RNAi selective for VEGF pathway genes is very beneficial for the treatment of NV disease. The compositions and methods of the present invention meet these needs. The present invention includes nucleic acid molecule compositions for use in modulating VEGF pathway gene expression and activity by RNA interference and reducing undesirable neovascularization, including tumor angiogenesis, and such nucleic acid molecules It relates to methods and compositions. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2018225873-A1 |
priorityDate | 2007-10-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 214.