abstract |
Realization of increased apparent solubility, dissolution rate, decreased melting point, and decreased crystallinity of an active agent. This is achieved by using a mixed phase co-crystal material. The mixed phase co-crystal material of the active agent and one or more materials that allow the active agent to be improved to a new physical / crystalline form with unique properties useful for active agent delivery is a When suspended in water, it produces a supersaturated concentration of the active agent for a long time, which promotes in vivo absorption. These changes in the nature of the active agent are particularly advantageous for active agent delivery (eg, in oral dosage forms). [Selection figure] None |