| abstract |
Novel polypeptides and biosynthetic pathways. It can be used to produce monatin from glucose, tryptophan, indole-3-lactic acid, indole-3-pyruvate, and 2-hydroxy 2- (indol-3-ylmethyl) -4-ketoglutaric acid Methods and compositions are provided. The method is also disclosed for the production of indole-3-pyruvate and 2-hydroxy 2- (indole-3-ylmethyl) -4-ketoglutarate intermediate. Provided compositions include nucleic acid molecules, polypeptides, chemical structures, and cells. The methods include in vitro and in vivo processes, and the in vitro methods include chemical reactions. [Selection figure] None |