abstract |
The present invention provides a composition for reducing postoperative complications of cardiopulmonary bypass (CPB) surgery. A composition comprising an effective amount of a methylol transfer agent selected from the group consisting of taurolidine, taurultam, and mixtures thereof, from before CPB surgery, during CPB surgery, after CPB surgery, and combinations thereof Administered during a time period selected from the group consisting of a taurolidine solution or a 2% taurolidine solution, administered in a dose of 250 ml, and following the surgery, the dose is reduced to 1 at 12 hour intervals. Administer twice a day. [Selection figure] None |