| abstract |
【Task】 The present invention provides a novel N-salicylamino acid derivative useful for the prevention and / or treatment of blood coagulation diseases. [Solution] Formula (i) [Chemical 1] [Where: R 1 , R 2 and R 3 each independently represent a hydrogen atom, a halogen atom, etc .; R 4 represents a hydrogen atom, a C 1-4 alkyl group, or a hydroxy C 1-4 alkyl group; R 5 and Each R 6 independently represents a hydrogen atom or a C 1-4 alkyl group; X is a C 6-10 aryl group optionally substituted with a substituent selected from the substituent group α, 5 to 10 Y represents -CO-, an oxygen atom-, etc .; Z represents -CH- or a nitrogen atom. Or a pharmacologically acceptable salt thereof. [Selection figure] None |