| abstract |
Compositions and methods related to variable lymphocyte receptors (VLRs) are provided. Disclosed are compositions and methods related to variable lymphocyte receptors (VLRs). The present invention comprises a single comprising an N-terminal leucine-rich repeat (LRRNT), one or more leucine-rich repeats (LRR) (referred to herein as an internal LRR), a C-terminal leucine-rich repeat (LRRRCT), and a linking peptide. A released polypeptide is provided, wherein the connecting peptide contains an alpha helix. The length of the polypeptide can include as few as about 130 amino acids or as many as about 225 amino acids. [Selection figure] None |