| abstract |
Disclosed are a compound that modulates the function of a TRPV1 receptor, a TRPV1 receptor antagonist, and a preventive and / or therapeutic agent for a disease involving TRPV1 receptor, including pain. In the research on the mechanism of analgesia, a receptor (TRPV1 receptor) of capsaicin (8-methyl-N-vanillyl-6-nonanamide), which is a main pungent component of chili pepper, has attracted attention. Formula (I), a novel receptor antagonist , A salt thereof, a solvate thereof, and a pharmaceutical composition containing these as active ingredients. [Selection figure] None |