| abstract |
The function of a polymerized 2,2,6,6-tetramethylpiperidinooxy radical (TEMPO) is enhanced, and at the same time, among low-molecular antioxidants other than TEMPO, in particular, poorly water-soluble. Therefore, the application field is limited and the provision of a composition with an enhanced function of an antioxidant whose effect is limited is provided. A composition comprising a low molecular weight antioxidant and a polymerized cyclic nitroxide radical compound. A composition in which a polymerized cyclic nitroxide radical compound is in the form of a polymer micelle, and a low-molecular antioxidant is encapsulated in the polymer micelle. This composition is useful for treating or preventing a disease or disorder mediated by or involving active oxygen or radical species. [Selection figure] None |