| abstract |
[Object] To provide an Arf6 gene loss-of-function animal, a method of examining a tumor, and a method of screening a tumor therapeutic agent An Arf6 gene loss-of-function animal, a transgenic animal having a Cre gene controlled by a promoter of a gene specifically expressed in vascular endothelial cells, a promoter of a gene specifically expressed in vascular endothelial cells is a Tie2 gene A tumor therapeutic agent comprising a promoter, an Arf6 inhibitor as an active ingredient, a tumor testing method using an Arf6 gene-deficient animal, and a tumor therapeutic drug screening method. [Selection figure] None |