abstract |
An object of the present invention is to increase the solubility of a poorly water-soluble anticancer agent in water without causing adverse side effects such as a hypersensitivity reaction, to maintain a high drug blood concentration, and to accumulate the drug in a tumor tissue at a high concentration. Of pharmaceutical preparations that enhance the pharmacological effects of allergic anticancer agents and reduce side effects. [MEANS FOR SOLVING PROBLEMS] A novel block copolymer that can serve as a drug carrier that does not exhibit harmful side effects such as hypersensitivity reactions, micelles, and a water-insoluble anticancer agent, particularly paclitaxel, in an amount necessary for the treatment of diseases. Micellar preparation that can be incorporated into micelles without binding and can enhance the solubility of the drug in water, maintains a high blood concentration with the micelle preparation as a medicinal ingredient, exhibits stronger medicinal properties, has toxicity Anticancer agent to alleviate. [Selection figure] None |