| abstract |
Kind Code: A1 The present invention provides use of a radiosensitive liposome as a carrier for therapeutic substance (s) and diagnostic substance (s), a method for producing the radiosensitive liposome, and a method for treating diseases such as cancer. A liposome delivery body comprising an appropriate liposome-forming lipid and a polymerizable colipid, wherein the fraction of the polymerizable colipid is polymerized upon exposure to ionizing radiation, thereby destabilizing the liposome membrane. Liposome delivery body. Due to the destabilization of the liposome, the contents of the liposome leak out. Also contemplated are methods of diagnosing and treating symptoms and diseases that respond to the liposome-encapsulated or associated substance. [Selection figure] None |