| abstract |
Disclosed is a method for identifying a material to be administered externally that is suitable as an active ingredient of cosmetics and the like (including quasi-drugs), a material identified by the identification method, and a composition comprising the material Offer things. [Solution] In a method for identifying a material to be administered for external use, an antibacterial peptide production promoting effect, particularly, a method for identifying a material to be administered for external use with β-defensin 1 gene (hBD1 mRNA) expression promoting effect as an index is established. By doing so, the raw material which has the novel action mechanism suitable for skin barrier function improvement, and has the skin barrier function improvement effect | action by the antimicrobial peptide production promotion effect | action, The composition containing the said material. [Selection] Figure 1 |