Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b9cafc17699713db7172dc81a3749fe1 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-55577 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-39 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0019 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-04 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-39 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P37-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-10 |
filingDate |
2011-05-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d4dad1352f46371b10ab73f8a6a994a8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_346036f3adad8799933afd89b7acf5c3 |
publicationDate |
2011-08-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
JP-2011162559-A |
titleOfInvention |
Composition comprising adjuvant QS-21 and polysorbate or cyclodextrin as excipient |
abstract |
Certain novel compositions of the adjuvant saponin QS-21 having improved properties are described. The composition of the present invention comprises (1) a reduction in the cytolytic activity of QS-21, (2) an improvement in the tolerability of a QS-21-containing preparation in humans or other animals, and (3) QS-21. Designed for stabilization from alkaline hydrolysis of and / or (4) maintaining high adjuvant efficacy of QS-21 products. These compositions can be used with vaccines comprising proteins or peptides, polysaccharides, lipids or nucleic acids. [Selection figure] None |
priorityDate |
1997-08-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |