http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2011155986-A
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_01f6ebfd35f3439dc94215e683d0c614 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6869 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
filingDate | 2011-04-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e06e8baee5af65cc703ab6ff28409be2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d2b9435f74ff9a7dc1080767643d2ae5 |
publicationDate | 2011-08-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | JP-2011155986-A |
titleOfInvention | Methods for making and sequencing modified polynucleotides |
abstract | The present invention provides a novel method for sequencing nucleic acids (eg, DNA), as well as improved methods for performing direct sequencing of nucleic acids (eg, DNA). At least one primer is annealed to a template polynucleotide sequence and the primer is extended in the presence of one or more nucleoside triphosphates to produce a modified polynucleotide sequence. At least one of the nucleoside triphosphates has been modified and the modified nucleotide sequence comprises a phosphorothiolate linkage. A modified polynucleotide sequence comprising a 3 ′ phosphorothiolate linkage or a modified polynucleotide sequence comprising a 5 ′ phosphorothiolate linkage is generated. [Selection figure] None |
priorityDate | 2005-06-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 208.