| abstract |
【Task】 To provide a solid dosage formulation that provides controlled release of the drug. [Solution] A central tablet comprising a drug dispersed in a first controlled release base, from which a base release of the drug is relatively slow, and a second controlled release base formed over the central tablet A solid dosage formulation comprising a coating comprising tramadol dispersed therein and having a relatively fast release rate of tramadol therefrom. [Selection] Figure 1 |