abstract |
The present invention provides a method for suppressing the bitter taste of a drug in producing an orally rapidly disintegrating tablet. SOLUTION: The use of (a) a granule containing a bitter-tasting drug and an excipient and not inhibiting bitterness, and (b) a granule containing a water-soluble saccharide, thereby reducing the bitterness of the drug. Suppress. (However, the case where the drug having a bitter taste is pravastatin sodium, sildenafil citrate, or cetraxate hydrochloride). Furthermore, it is preferable to blend (c) a refreshing agent and a sweetening agent with one or both of (a) and (b). [Selection figure] None |